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王志梅
 
发布时间: 2017-10-09         浏览次数: 13


【个

·姓名:王志梅

·性别:

·出生年月:1982.03

·民族:汉

·职称:工程师

·学历:博士

·联系电话:13813952952

·电子信箱:wangzm@seu.edu.cn

课题组网址:http://pcseu.gotoip2.com/index.html

【研究方向

铂类抗肿瘤药物的仪器分析



2001.9-2005.7

中国药科大学制药工程专业,获学士学位

2005.9-2008.7

中国药科大学药物分析专业,硕士学位

2012.2-2016.12

中国药科大学制药工程专业,获博士学位

2008.7-至今

东南大学药物研究中心江苏省生物药物高技术研究重点实验室,东南大学分析测试中心,工程师

科研项目


论文及获奖

发表论文:

2016

  1. Wang ZM(王志梅), Yu HY, Gou SH, et al. Design, synthesis, and biological features of platinum(II) complexes with rigid steric hindrance [J]. Inorganic Chemistry, 2016, 55(9): 4519-4528.

  2. Wang ZM(王志梅), Wu M, Gou SH. Toward a better understanding of the oxaliplatin mode of action upon the steric hindrance of 1,2-diaminocyclohexane and its analogue [J]. Journal of Inorganic Biochemistry, 2016, 157: 1-7.

  3. Yu HY, Gou SH, Wang ZM(王志梅),et al. Toward overcoming cisplatin resistancevia sterically hindered platinum(II) complexes [J]. European Journal of Medicinal Chemistry, 2016, 114:141-152.

  4. Huang XC, Huang RZ, Gou SH, Wang ZM(王志梅), Liao ZX, and Wang HS. Combretastatin A-4 analogue: A dual-targeting and tubulin inhibitor containing antitumor Pt(IV) moiety with a unique mode of action.Bioconjugate Chemistry, 2016, 27(9): 2132-2148.


2014

  1. Zhao J, WenYL, ZhangW, Zhao D, Fan A, Zhang YJ, Deng SH, Wang X, Wang ZM(王志梅), Gou SH, Chen XJ. Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by inductively coupled plasma mass spectrometry [J]. Xenobiotica, 2014, 44(8): 757-762.

2012


  1. ZhaoJ, GouSH, Sun YY, Fang L, Wang ZM(王志梅). Antitumor platinum (II) complexes containing platinum based moieties of present platinum drugs and furoxan groups as nitric oxide donors: synthesis, DNA interaction and cytotoxicity [J]. Inorganic Chemistry, 2012, 51(19): 10317-10324.

  2. Zhao J, Gou SH,Sun YY, Yin RT, and WangZM(王志梅).Nitric oxide donors as potential anticancer agents [J].Chemistry-AEuropean Journal, 2012, 18(45): 14276-14281.



英文简历


PersonalInformation

·Name: Zhimei Wang

·Gender: female

·Date of Birth: 1982.03

·Nationality: Chinese

·Title: Dr.

·Degree: doctor

·Tel: 13813952952

·Email: wangzm@seu.edu.cn

Research

My current research interests focus on: analysis of anti-tumor drugs



Educational and Professional Experience

Education

Sep. 2001------Jun. 2005: China Pharmaceutica University,

Nanjing, P. R. China

Specialty: Pharmaceutical Engineering

Bachelor candidate

Sep. 2005------Jun. 2008: China Pharmaceutica University,

Nanjing, P. R. China

Specialty: Pharmaceutical Analysis

Mastercandidate

Feb. 2012------Dec. 2016: China Pharmaceutical University      

Nanjing, P. R. China

Specialty: Pharmaceutical Engineering

Doctor candidate

Professional Experience

Jul. 2008------present: Lecturer in Medicinal Chemistry

Pharmaceutical research center, Jiangsu Province Hi-Tech Key Laboratory for Bio-medical Research, Southeast University

Nanjing, P. R. China

Grant Activities


Publications and Awards

2016

  1. Wang ZM(王志梅), Yu HY, Gou SH, et al. Design, synthesis, and biological features of platinum(II) complexes with rigid steric hindrance [J]. Inorganic Chemistry, 2016, 55(9): 4519-4528.

  2. Wang ZM(王志梅), Wu M, Gou SH. Toward a better understanding of the oxaliplatin mode of action upon the steric hindrance of 1,2-diaminocyclohexane and its analogue [J]. Journal of Inorganic Biochemistry, 2016, 157: 1-7.

  3. Yu HY, Gou SH, Wang ZM(王志梅),et al. Toward overcoming cisplatin resistancevia sterically hindered platinum(II) complexes [J]. European Journal of Medicinal Chemistry, 2016, 114:141-152.

  4. Huang XC, Huang RZ, Gou SH, Wang ZM(王志梅), Liao ZX, and Wang HS. Combretastatin A-4 analogue: A dual-targeting and tubulin inhibitor containing antitumor Pt(IV) moiety with a unique mode of action.Bioconjugate Chemistry, 2016, 27(9): 2132-2148.


2014

  1. Zhao J, WenYL, ZhangW, Zhao D, Fan A, Zhang YJ, Deng SH, Wang X, Wang ZM(王志梅), Gou SH, Chen XJ. Investigation on pharmacokinetics, tissue distribution and excretion of a novel platinum anticancer agent in rats by inductively coupled plasma mass spectrometry [J]. Xenobiotica, 2014, 44(8): 757-762.

2012

  1. ZhaoJ, GouSH, Sun YY, Fang L, Wang ZM(王志梅). Antitumor platinum (II) complexes containing platinum based moieties of present platinum drugs and furoxan groups as nitric oxide donors: synthesis, DNA interaction and cytotoxicity [J]. Inorganic Chemistry, 2012, 51(19): 10317-10324.

  2. Zhao J, Gou SH,Sun YY, Yin RT, and WangZM(王志梅).Nitric oxide donors as potential anticancer agents [J].Chemistry-AEuropean Journal, 2012, 18(45): 14276-14281.



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