浅谈趋化因子 CXCL12 在冠心病及肿瘤中的研究现状
刘佩岩 王凤玲∗
(佳木斯大学,黑龙江 佳木斯 154000)
Research Status of Chemokine CXCL12 in Coronary Heart Disease and Tumor
Liu Peiyan; Wang Fengling∗;
(Jiamusi University,Heilongjiang Jiamusi 154000)
摘要:
趋化因子CXCL12及其配体CXCR4和CXCR7通过多种途径参与许多疾病的发生发展,例如冠心病、肿瘤。趋化因子CXCL12因其复杂的致病机制已经成为近几年的研究热点,本文就近几年关于CXCL12及其受体在冠心病及肿瘤中的研究进行综述。
关键词：CXCL12；CXCR4；CXCR7；冠心病；肿瘤；
Abstract：
The chemokine CXCL12 and its ligands CXCR4 and CXCR7 are involved in the occurrence and development of many diseases, such as coronary heart disease and tumor, through a variety of pathways. The chemokine CXCL12 has become a research hotspot in recent years due to its complex pathogenic mechanism. In this paper, the research on CXCL12 and its receptor in coronary heart disease and tumor in recent years is reviewed.
Keywords：CXCL12; CXCR4; CXCR7; coronary heart disease; tumor;