doi:10.16597/j.cnki.issn.1002-154x.2023.02.012
甲磺酸萘莫司他的合成及药理作用研究进展
黄姗珊 魏洪福 王寒雪 喻浩耘 张美杰 王令 袁孝雪 史成阳 李进京∗
(佳木斯大学 药学院,黑龙江 佳木斯 154007)
Research Progress on Synthesis and Pharmacological Action of Nafolimus Mesylate
Huang Shanshan; Wei Hongfu; Wang Hanxue; Yu Haoyun; Zhang Meijie; Wang Ling; Yuan Xiaoxue; Shi Chengyang; Li Jinjing ∗;
(College of Pharmacy, Jiamusi University, Heilongjiang Jiamusi, 154007)
摘要:
甲磺酸萘莫司他作为蛋白酶抑制剂,主要应用于急性胰腺炎的治疗。作者综述了近些年甲磺酸萘莫司他合成的方法,并对其药理作用进行了总结,以期为今后研究甲磺酸萘莫司他提供更加全面的依据。
关键词：甲磺酸萘莫司他；有机合成；药理作用；
Abstract：
As a protease inhibitor, nafolimus mesylate is used in the treatment of acute pancreatitis. The synthetic methods and pharmacological effects of nafolimus mesylate in recent years are summarized. More comprehensive basis for the study of nafolimus mesylate in the future is provided.
Keywords：nafolimus mesylate; organic synthesis; pharmacologic action;