doi:10.16597/j.cnki.issn.1002-154x.2024.01.009
黄芪多糖提取与生物活性的研究进展
段淼慧1 张志强2∗
(1. 云南省滇南中心医院(红河州第一人民医院),蒙自 661100; 2. 佳木斯大学,佳木斯 154007)
Research Progress of Astragalus Polysaccharide Extraction and Biological Activity
Duan Miaohui 1 Zhang Zhiqiang 2∗
(1. Yunnan Diannan Central Hospital (First People's Hospital of Honghe Prefecture), Mengzi 661100, China; 2. Jiamusi University, Jiamusi 154007, China)
摘要:
黄芪(AR)是一种具有悠久临床应用历史的传统中药,作为药食用于改善和治疗各种疾病,以活脾补气。 其主 要成分是黄芪多糖(APS)、黄酮类化合物、皂苷类化合物、生物碱等。 APS 来源于 AR 的干根,具有改善或治疗不同疾病 的巨大潜力。 作者综述了 APS 的提取方法与生物活性的研究进展,总结了几种可以提取该成分的技术,包括微波辅助、 酶促、水、超声和回流提取。 此外,作者还总结了 APS 的生物活性,如抗炎、抗氧化、抗肿瘤和抗病毒等,以期为 APS 的更好开发利用提供理论支持。
关键词：黄芪多糖 提取方法 生物活性 药理学特性；
Abstract：
Astragalus membranaceus ( AR) is a traditional Chinese medicine with a long history of clinical application. It is used as medicine to improve and treat various diseases to invigorate the spleen and tonify the qi. Its main components are Astragalus polysaccharides(APS), flavonoids, saponins, alkaloids, etc. APS is an important bioactive component derived from the dried root of AR, which has various pharmacological properties. APS has a great potential to improve or treat different diseases. The aim of this paper is to provide a comprehensive review of the research progress on the extraction methods and biological activities of APS. Several techniques are available to extract this component, among which microwave-assisted, enzymatic, aqueous, ultrasonic and reflux extraction are the most commonly used. This paper also summarizes the biological activities of APS, such as antiinflammatory, antioxidant, antitumor and antiviral activities. It is expected to provide theoretical support for better development and utilization of APS.
Keywords：Astragalus polysaccharide; extraction method; biological activity; pharmacological properties;