胡娟（博导）

发布者：陈飞虹发布时间：2021-05-12浏览次数：5129

【个人资料】

·姓名：胡娟

·性别： 女

·民族：汉

·学历： 博士

·办公地点：九龙湖校区化工新楼317

·联系电话：

·联系邮箱 ：hujuan@seu.edu.cn

【研究方向】

生化分析和单分子检测研究

【经历】

胡娟，博士，上岗研究员，博士生导师。

【科研项目】

主持完成国家自然科学基金面上项目和青年科学基金项目。

【论文及获奖】

1. Yan Zhang, Chen Wang, Xiaoran Zou, Xiaorui Tian, Juan Hu,* Chun-yang Zhang,* Simultaneous Enzyme-Free Detection of Multiple Long Noncoding RNAs in Cancer Cells at Single-Molecule/Particle Level. Nano Letters, 2021, 21(10), 4193-4201.

2. Chen-chen Li, Yue-hong Dong, Xiaoran Zou, Xiliang Luo,* Dazhong Shen,* Juan Hu,* Chun-yang Zhang,* Label-Free and Template-Free Chemiluminescent Biosensor for Sensitive Detection of 5 Hydroxymethylcytosine in Genomic DNA. Analytical Chemistry, 2021, 93(4), 1939-1943.

3. Juan Hu, Wen Liu, Jufeng Wang, Jian-Ge Qiu,* Chun-yang Zhang,* Simple Mix-and-Read Assay with Multiple Cyclic Enzymatic Repairing Amplification for Rapid and Sensitive Detection of DNA Glycosylase. Analytical Chemistry, 2021, 93(18), 6913-6918.

4. Juan Hu, Jie Yao, Jufeng Wang, Li-yuan Pan, Jian-Ge Qiu,* Chun-yang Zhang,* A single quantum dot-based fluorescence resonance energy transfer biosensor for antibody-free detection of ten-eleven translocation 1. Chemical Communications, 2021, 57(29), 3543-3546.

5. Juan Hu, Li-yuan Pana, Yueying Li, Xiaoran Zou, Bing-jie Liu, BingHua Jiang,* Chun-yang Zhang,* Deacetylation-activated construction of single quantum dot-based nanosensor for sirtuin 1 assay. Talanta, 2021, 224, 121918.

6. Junjie Zhang, Xianwei Su, Ao Qi, Lulu Liu, Lijian Zhang, Yu Zhong, Simin Xu, Ximei Liu, Juan Hu,* Yusen Chen,* Chun-yang Zhang,* Chun Cai,* Metabolomic profiling of fatty acid biomarkers for intracerebral hemorrhage stroke. Talanta, 2021, 222, 121679.

7. Chen-chen Li, Hui-yan Chen, Juan Hu,* Chun-yang Zhang,* Rolling circle amplification-driven encoding of different fluorescent molecules for simultaneous detection of multiple DNA repair enzymes at the single-molecule level. Chemical Science, 2020, 11(22), 5724-5734.

8. Yueying Li, Wen Liu, Qinfeng Xu, Juan Hu,* Chun-yang Zhang,* Construction of a sensitive protease sensor with DNA-peptide conjugates for single-molecule detection of multiple matrix metalloproteinases. Biosensors and Bioelectronics, 2020, 169, 112647.

9. Juan Hu, Yang Liu, Chun-yang Zhang,* Construction of a single quantum dot nanosensor with the capability of sensing methylcytosine sites for sensitive quantification of methyltransferase. Nanoscale, 2020, 12(7), 4519-4526.

10. Juan Hu, Ming-hao Liu, Chun-yang Zhang,* Construction of Tetrahedral DNA-Quantum Dot Nanostructure with the Integration of Multistep Forster Resonance Energy Transfer for Multiplex Enzymes Assay. ACS Nano, 2019, 13(6), 7191-7201.

11. Chen-chen Li, Wan-xin Liu, Juan Hu,* Chun-yang Zhang,* A single quantum dot-based nanosensor with multilayer of multiple acceptors for ultrasensitive detection of human alkyladenine DNA glycosylase. Chemical Science, 2019, 10(37), 8675-8684.

12. Lin Cui, Juan Hu, Meng Wang, Chen-chen Li, Chun-yang Zhang,* Label-Free and Immobilization-Free Electrochemical Magnetobiosensor for Sensitive Detection of 5-Hydroxymethylcytosine in Genomic DNA. Analytical Chemistry, 2019, 91(2), 1232-1236.

13. Juan Hu, Ming-hao Liu, Chun-yang Zhang,* Integration of isothermal amplification with quantum dot-based fluorescence resonance energy transfer for simultaneous detection of multiple microRNAs. Chemical Science, 2018, 9(18), 4258-4267.

14. Juan Hu, Ming-hao Liu, Ying Li, Bo Tang,* Chun-yang Zhang,* Simultaneous sensitive detection of multiple DNA glycosylases from lung cancer cells at the single-molecule level. Chemical Science, 2018, 9(3), 712-720.

15. Chen-chen Li, Juan Hu, Mengfei Lu, Chun-yang Zhang,* Quantum dot-based electrochemical biosensor for stripping voltammetric detection of telomerase at the single-cell level. Biosensors and Bioelectronics, 2018, 122, 51-57.

16. Lin Cui, Juan Hu, Chen-chen Li, Cheng-ming Wang, Chun-yang Zhang,* An electrochemical biosensor based on the enhanced quasi-reversible redox signal of prussian blue generated by self-sacrificial label of iron metal-organic framework. Biosensors and Bioelectronics, 2018, 122, 168-174.

17. Lin Cui, Juan Hu, Meng Wang, Xing-kang Diao, Chen-chen Li, Chun-yang Zhang,* Mimic Peroxidase- and Bi2S3 Nanorod-Based Photoelectrochemical Biosensor for Signal-On Detection of Polynucleotide Kinase. Analytical Chemistry, 2018, 90(19), 11478-11485.

18. Dandan Zhang, Juan Hu, Xiao-yun Yang, Yanxia Wu, Wenmei Su, Chun-yang Zhang,* Target-initiated synthesis of fluorescent copper nanoparticles for the sensitive and label-free detection of bleomycin. Nanoscale, 2018, 10(23), 11134-11142.

19. Juan Hu, Yueying Li, Ying Li, Bo Tang,* Chun-yang Zhang,* Single Quantum Dot-Based Nanosensor for Sensitive Detection of O-GIcNAc Transferase Activity. Analytical Chemistry, 2017, 89(23), 12992-12999.

20. Juan Hu, Zi-yue Wang, Chen-chen Li, Chun-yang Zhang,* Advances in single quantum dot-based nanosensors. Chemical Communications, 2017, 53(100), 13284-13295.

21. Si-qiang Huang, Juan Hu, Guichi Zhu, Chun-yang Zhang,* Sensitive detection of point mutation using exponential strand displacement amplification-based surface enhanced Raman spectroscopy. Biosensors and Bioelectronics, 2015, 65, 191-197.

22. Li-Ping Ye, Juan Hu, Li Liang, Chun-yang Zhang,* Surface-enhanced Raman spectroscopy for simultaneous sensitive detection of multiple microRNAs in lung cancer cells. Chemical Communications, 2014, 50(80), 11883-11886.

23. Juan Hu, Chun-yang Zhang,* Multiplex detection of lung cancer cells at the single-molecule level. Chemical Communications, 2014, 50(88), 13581-13584.

24. Juan Hu, Chun-yang Zhang,* Simple and Accurate Quantification of Quantum Yield at the Single-Molecule/Particle Level. Analytical Chemistry, 2013, 85 (4), 2000-2004.

25. Ya-ping Zeng, Juan Hu, Yi Long, Chun-yang Zhang,* Sensitive Detection of DNA Methyltransferase Using Hairpin Probe-Based Primer Generation Rolling Circle Amplification-Induced Chemiluminescence. Analytical Chemistry, 2013, 85(12), 6143-6150.

26. Yan Zhang, Juan Hu, Chun-yang Zhang,* Sensitive Detection of Transcription Factors by Isothermal Exponential Amplification-Based Colorimetric Assay. Analytical Chemistry, 2012, 84(21), 9544-9549.

27. Juan Hu, Chun-yang Zhang,* Single base extension reaction-based surface enhanced Raman spectroscopy for DNA methylation assay, Biosensors and Bioelectronics, 2012, 31(1), 451-457.

28. Chun-yang Zhang,* Juan Hu, Single Quantum Dot-Based Nanosensor for Multiple DNA Detection. Analytical Chemistry, 2010, 82(5), 1921-1927.

29. Juan Hu, Chun-yang Zhang,* Sensitive Detection of Nucleic Acids with Rolling Circle Amplification and Surface-Enhanced Raman Scattering Spectroscopy, Analytical Chemistry, 2010, 82(21), 8991-8997.

30. Juan Hu, Peng-Cheng Zheng, Jian-Hui Jiang, Guo-Li Shen, Ru-Qin Yu,* Guo-Kun Liu,* Electrostatic Interaction Based Approach to Thrombin Detection by Surface-Enhanced Raman Spectroscopy, Analytical Chemistry, 2009, 81 (1), 87-93.